產品詳情
簡單介紹:
NeuralPrecursorCellExpressed,DevelopmentallyDown-Regulated9(NEDD9)(MiddleRegion)Peptide
詳情介紹:
Blocked Antibody | anti-NEDD9 antibody (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9) (Middle Region) (ABIN2784462) |
Characteristics | This is a synthetic peptide designed for use in combination with anti-NEDD9 antibody (Catalog #: ARP51211_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
Purification | Purified |
Background |
Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers. Alias Symbols: CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2 Protein Interaction Partner: FZR1,SMAD3,ABL1,BCAR1,BCAR3,CDH1,CHAT,CRK,CRKL,DIMT1L,ELSPBP1,FYN,ID2,ITCH,LCK,LYN,MICAL1,NCK1,NEDD9,PTK2,PTK2B,PTPN11,PTPN12,PXN,RAPGEF1,SH2D3C,SMAD1,SMAD2,SMAD3,TCF3,TRIP6,ZYX,ABL1,BCAR1,BCAR3,CDH1,CRK,CRKL,ELSPBP1,FYN,ID2,ITCH,LCK,LYN,MICAL1,NCK1,NEDD9,PTK2,PTK2B,PTPN12,PXN,RAPGEF1,SH2D3C,SMAD1,SMAD2,SMAD3,TRIP6,ZYX Protein Size: 834 |
Molecular Weight | 93 kDa |
Gene ID | 4739 |
NCBI Accession | NM_006403, NP_006394 |
UniProt | Q14511 |
Research Area | Signaling, Cell Cycle |
Application Notes | Each Investigator should determine their own optimal working dilution for specific applications. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
Concentration | 1 mg/mL |
Buffer | Final peptide concentration is 1 mg/mL in PBS. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |