產品詳情
簡單介紹:
Stat3InhibitorI,S3I-201
詳情介紹:
Purpose | A Stat3 Inhibitor |
Characteristics | Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 +/- 33 μM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo. |
Purity | ≥ 97?% by HPLC |
Chemical Name | 2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201 |
Formula | C??H??NO?S |
Permeability | Cell-permeable |
Solubility | DMSO (10 mg/ml) |
Molecular Weight | 365.36 g/mol |
CAS-No | 501919-59-1 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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