產(chǎn)品詳情
簡單介紹:
DPPIVInhibitor,NVPDPP728
詳情介紹:
Purpose | A potent DPP IV Inhibitor |
Characteristics | A potent, selective, reversible, and slow binding dipeptidyl peptidase IV inhibitor (IC?? = 14 nM). Displays >15,000 fold selectivity over DPP-II and a range of Proline-cleaving proteases. Displays anti-diabetic activity in vivo, improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, and augments insulin secretion and GLUT-2 levels. |
Purity | ≥ 98?% by HPLC |
Chemical Name | 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride |
Formula | C??H??N?O.2HCl |
Permeability | Cell-permeable |
Solubility | DMSO (approx. 100 mM) or EtOH (approx. 100 mM) |
Molecular Weight | 371.27 g/mol |
CAS-No | 247016-69-9 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and moisture |
Storage | -20 °C |
Expiry Date | 48 months |
Supplier Images |
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