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  • 產品名稱：rAPETx2

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簡單介紹：
rAPETx2
詳情介紹：
Sequence GTACSCGNSK GIYWFYRPSC PTDRGYTGSC RYFLGTCCTP AD1.
Specificity APETx2 inhibits ASIC3 channels2.
Characteristics Source: Anthopleura elegantissima (Sea anemone)1.
Molecular formula: C196H286N54O61S6.
Disulfide bonds between Cys4-Cys37, Cys6-Cys30, and Cys20-Cys38 1.
Purity > 98 %
Molecular Weight 4561
Application Notes 10 nM-3M
Comment

Toxin APETx2
Restrictions For Research Use only
Format Lyophilized
Reconstitution Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Concentration after reconstitution: Dissolving 50g in 1.096ml will provide a stock solution of 10 M.
Handling Advice Soluble in Water.
Product cited in: Chagot, Escoubas, Diochot, Bernard, Lazdunski, Darbon: "Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels." in: Protein science : a publication of the Protein Society, Vol. 14, Issue 8, pp. 2003-10, 2005 (PubMed).

Diochot, Baron, Rash, Deval, Escoubas, Scarzello, Salinas, Lazdunski: "A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons." in: The EMBO journal, Vol. 23, Issue 7, pp. 1516-25, 2004 (PubMed).